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The polymorphism of the vitamin D-binding protein (Gc); Isoelectric focusing in 3 M urea as additional method for identification of genetic variants

Identifieur interne : 00E090 ( Main/Exploration ); précédent : 00E089; suivant : 00E091

The polymorphism of the vitamin D-binding protein (Gc); Isoelectric focusing in 3 M urea as additional method for identification of genetic variants

Auteurs : J. Constans [France] ; H. Cleve [Allemagne] ; D. Dykes [États-Unis] ; M. Fischer [Allemagne] ; R. L. Kirk [Australie] ; S. S. Papiha [Royaume-Uni] ; W. Schffran [Suisse] ; R. Scherz [Suisse] ; M. Thymann [Danemark] ; W. Weber [Allemagne]

Source :

RBID : ISTEX:AF94A01210EE864EC7BEBB5722B98EEA1C810560

English descriptors

Abstract

Summary: Since the last report numerous new DBP (Gc) variants have been observed; at present a total of 84 different mutants can be distinguished. Several of them have similar electrophoretic mobilities and/or isoelectric points by conventional isoelectric focusing (IEF). IEF in polyacrylamide gels in the presence of 3 M urea is a convenient and effecient method for the detection of hidden variation.

Url:
DOI: 10.1007/BF00286658


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<title xml:lang="en">The polymorphism of the vitamin D-binding protein (Gc); Isoelectric focusing in 3 M urea as additional method for identification of genetic variants</title>
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<term>Ethnic origin</term>
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<div type="abstract" xml:lang="en">Summary: Since the last report numerous new DBP (Gc) variants have been observed; at present a total of 84 different mutants can be distinguished. Several of them have similar electrophoretic mobilities and/or isoelectric points by conventional isoelectric focusing (IEF). IEF in polyacrylamide gels in the presence of 3 M urea is a convenient and effecient method for the detection of hidden variation.</div>
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